The A1 Mini is Bambu's cheapest printer. It's excellent for PLA hobbyists, miniature painters, and anyone who wants a reliable plug-and-play machine without spending much. The P2S is Bambu's newer enclosed P-series printer; the older P1S ($369) is the cheapest enclosed Bambu. The P2S can do everything the A1 Mini can and more, with a bigger build plate and support for engineering materials.
The key question is whether you know what you want to print. PLA and small objects? A1 Mini. Anything bigger, faster, or requiring an enclosure? P2S.